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Societal stigma and mistreatment in healthcare among gender minority people: a cross-sectional study



Gender minority (GM; individuals whose gender is not aligned with that traditionally associated with the sex that was assigned to them at birth) people have widely reported mistreatment in healthcare settings. Mistreatment is enacted by individuals within society who hold stigmatizing beliefs. However, the relationship between healthcare mistreatment and societal stigma (i.e., the degree to which society disapproves of GM people) is unclear and not measured consistently.


We analyzed data from 2,031 GM participants in The Population Research in Identity and Disparities for Equality (PRIDE) Study’s 2019 Annual Questionnaire to determine whether societal stigma was associated with participants’ past-year reports of mistreatment (defined as denial of healthcare services and/or lower quality care) in medical or mental healthcare settings. We created a proxy measure of societal stigma by incorporating variables validated in existing literature. Participants reported whether they had experienced mistreatment in medical and mental health settings independently.


Healthcare denial and/or lower quality care during the past year was reported by 18.8% of our sample for medical settings and 12.5% for mental health settings. We found no associations between the societal stigma variables and past-year reports of healthcare denial and/or lower quality care in medical or mental healthcare settings.


Although a high proportion of GM people reported past-year healthcare mistreatment in both medical and mental health settings, mistreatment had no relationship with societal stigma. Factors other than societal stigma may be more important predictors of healthcare mistreatment, such as healthcare workers’ knowledge of and attitudes toward GM people. However, other measures of societal stigma, or different types of mistreatment, may show stronger associations. Identifying key factors that contribute to mistreatment can serve as targets for intervention in communities and healthcare settings.


Gender minority (GM; individuals whose gender is not aligned with that traditionally associated with the sex assigned to them at birth) people report experiencing a broad range of discriminatory practices in healthcare settings. These experiences include: deficits in healthcare provider knowledge about the unique health needs of GM people, denial of healthcare services, verbal harassment, and physical violence [1,2,3,4]. Similar patterns have been identified in mental health settings [3, 5]. Lack of provider competence in caring for GM people and direct mistreatment can have deleterious effects on health and healthcare access, including avoidance of necessary healthcare services [6,7,8,9,10]. Avoidance of healthcare services among GM people has been associated with negative health outcomes such as poor self-reported general health, substance use [11] and increased risk of seeking gender-affirming treatments (e.g., hormone replacement therapy) from outside of the traditional healthcare system, such as from illicit sources [2, 12]. While the risks posed by healthcare mistreatment have been broadly examined, the association of healthcare mistreatment and societal stigma, or the degree to which society disapproves of GM people [13], is less understood.

While structural stigma has been defined as “societal norms and institutional policies that constrain access to resources” [14], we propose that this is actually two constructs: structural and societal stigma. Structural stigma is “institutional policies that constrain access to resources” [14]. Societal stigma, or the degree to which society disapproves of GM people, is determined by cultural norms and standards [13, 15]. Another stigma – interpersonal stigma – relates to direct forms of stigma such as harassment and violence. Whether the broader, dominant society accepts or denies the existence and rights of a marginalized group dictates the policies or laws, their implementation and enforcement, resources alotted to the marginalized group, and individual behaviors deemed socially permissable. Measurement of societal stigma can be viewed as a reflection of other stigma constructs described by Link & Phelan [16]. This relationship is reciprocal; underlying attitudes toward GM people can influence structural, interpersonal, and individual stigma, and they can also influence societal stigma (Fig. 1).

Fig. 1
figure 1

Societal Stigma and Stigma Conceptual Model (adapted from Hughto White et al., 2015)

Objective measures of societal stigma, or negative societal attitudes toward GM people, remain absent in scientific literature. Proxy measures of societal stigma in the United States (US) may include state-level policies [17], but the use of summed sexual and gender minority-related (SGM; people whose sexual orientation is not heterosexual and/or individuals whose gender is not aligned with that traditionally associated with the sex assigned to them at birth) state-level policies [18, 19] may be a more accurate reflection of a state’s societal stigma since the action to pass a number of protective policies may indicate the prioritization of GM inclusivity at the state-level. Another US state-level proxy for societal stigma may be the percent of a state that voted for the Republican party candidate in a recent presidential election [20], where greater percentages were associated with greater reports of healthcare services denial among GM participants. These variables may be applied to represent the attitudes toward GM people in a given area. These proxy measures of societal stigma have been associated with a range of outcomes such as poor mental health [17] and greater reports of healthcare services denial [20]. However, little is known about the association between societal stigma and specific forms of interpersonal stigma, such as healthcare mistreatment, defined here as denial of healthcare services or provision of inequitable care. A stronger understanding of this relationship could inform changes in healthcare system to increase equitable healthcare delivery.


The purpose of our study was to compare the relationship between selected proxy measures of societal stigma and past-year healthcare mistreatment (i.e., healthcare service denial and/or lower quality care) in medical or mental healthcare settings in a diverse national sample of GM adults in the US. Proxy measures that reflect multiple types of enacted social attitudes were selected for these analyses. We hypothesized that at least one proxy variable for societal stigma (i.e., lower State LGBT + Business Climate Index scores, living in a lower population density area, or lower access to GM inclusive healthcare) would be associated with healthcare service denial and/or lower quality care in medical or mental healthcare settings.

Data were collected within the 2019 Annual Questionnaire of The Population Research in Identity and Disparities for Equality (PRIDE) Study, a national, longitudinal cohort study of sexual and gender minority people who reside in the US. Please see Lunn et al. for detailed description of The PRIDE Study [21]. Briefly, The PRIDE Study is a community-engaged research study with an active Participant Advisory Committee that reviewed and informed the adaptations of measures used in the survey to be inclusive of SGM communities. This committee reviewed and approved the study described here. An extensive recruitment effort for The PRIDE Study included PRIDEnet partners (community partnerships and stakeholders), online communications (e.g., blog posts, newsletters, advertising on social media), in-person outreach at conferences and events, the distribution of The PRIDE Study promotional items, and word-of-mouth. Eligible participants included individuals who were 18 years and older, resided in the US or its territories, self-identified as LGBTQ + or as a sexual and/or gender minority person, and who took 2019 Annual Questionnaire measures outlined in these analyses between June 2019 and May 2020. The GM sample was retained for these analyses, meaning participants who endorsed a gender identity that aligned with the sex that they were assigned at birth were dropped (n = 3,629).



Demographics queried of participants included age, race/ethnicity, sexual orientation, gender identity, highest level of education completed, and individual gross income. Age was calculated by subtracting participants’ birth date, obtained upon study enrollment, from the date that the survey was first accessed. Race/ethnicity were measured with a categorical variable (select all that apply). Participants reported sexual orientation with a select-all-that-apply approach that offered 10 options and an open text entry if their preferred label was not listed. Participants reported gender identity with a select-all-that-apply approach that offered 10 options and an open text entry to enter their preferred gender identity if their preferred label was not listed. Highest level of education was measured by an ordinal variable with 10 options ranging from “no schooling” to “Professional degree,” which we then coded as a 4-level variable (i.e., “no high school diploma,” “high school/GED graduate or some college,” “college degree [2- or 4-year],” and “graduate degree”). Individual income was measured by an ordinal 11-item variable ranging from $0 to >$100,000 (collapsed in Table 1). Differences in the experiences of stigma and health vary among different gender identities; therefore, participants were divided into three study population categories to capture the unique experiences [22,23,24]. Participants who described their gender as non-binary or “another gender identity not listed” were combined in a gender-expansive category. Participants who described their gender identity as transgender man or transgender woman remained in those two separate categories.

Table 1 Characteristics of The PRIDE Study 2019 Annual Questionnaire participants

Societal stigma

Three variables were used as proxy variables for societal stigma based on findings from previous analyses [15]. These items were matched to participants based on participant-reported Zone Improvement Plan (ZIP) code.

Population density- Participant ZIP code was converted to Rural-Urban Continuum Codes [25], which identified the population density where the participant resided. These codes were recoded to a single dichotomous variable, indicating urban (participant resides in a designated metropolitan county) and non-urban (participant resides in an area that is not designated as a metropolitan county).

State LGBT + Business Climate Index- Out Leadership, an organization aimed at connecting SGM business leaders, releases an annual report that provided an index on how SGM inclusive each state is to inform business leaders, organizations, and policymakers of “the costs created by polices that create minority stress” [26]. The LGBT + Business Climate Index incorporates data from the Movement Advancement Project, the United States Transgender Survey, The Williams Institute, the Bureau of Labor Statistics, and the United States Treasury to create a score for each state that ranges from 25 to 100 from points allotted from five domains: “Legal and Nondiscrimination Protections,” “Youth and Family Support,” “Political and Religious Attitudes,” “Health Access and Safety,” and “Work Environment and Employment.” A sensitivity analysis comparing the variable in continuous and ordinal forms was performed. No statistically meaningful difference was observed. Therefore, these scores were included as a single continuous variable to retain as much information as possible, where higher values indicate a more positive environment for SGM people.

Leaders in LGBTQ Healthcare Equality- The Human Rights Campaign (HRC) provides an annual Healthcare Equality Index report in which hospitals are scored by calculating the number of SGM-inclusive policies they implemented within four domains: “Patient-Centered Care,” “Patient Services and Support,” “Employee Benefits and Policies,” and “Community Engagement” [27]. The total possible score ranges from 0 to 100. A score of 100 gives a healthcare facility the designation of “Leader in LGBTQ Healthcare Equality.” The total estimated GM population in each state [28] was divided by the total number of healthcare facilities with the “Leader in LGBTQ Healthcare Equality” designation to create a continuous variable accounting for different estimated proportions of GM people in each state. A lower number indicates better access to inclusive care, or lower societal stigma as inclusive care is likely to be more valued where there is better access.

Proxy measures of societal stigma that incorporate sexual orientation in addition to gender identity in the development of their variables (i.e., State LGBT + Business Climate Index, Leaders in LGBTQ Healthcare Equality) were retained as developed. This is because the measures did not provide unique data for societal stigma as related to sexual orientation versus gender identity. Additionally, our GM sample (n = 2031) is comprised of almost 96% SM. Therefore, measurement of social climate in regard to both sexual orientation and gender identity are important to GM people’s experiences [29].

Healthcare service denial and/or lower quality of care

Healthcare mistreatment was measured by two dependent variables. Participants reported whether they had been refused healthcare services or given lower quality (a) medical or (b) mental healthcare in the past 12 months. If they reported ‘yes,’ they were then asked whether they attributed this experience to their gender identity and/or expression. A dichotomous variable was created for each healthcare setting, medical or mental health. Participants who did not access care in the past 12 months were excluded from analysis (n = 53).


Descriptive statistics were used for demographic variables and past-year medical and mental healthcare discrimination among the three gender identity categories: gender-expansive people, transgender men, and transgender women. In our analyses, where sexual orientation and race/ethnicity were included as covariates, each of the response options were dichotomously coded to account for multiple selections of race/ethnicity or sexual orientation.

Logistic regression analysis was used to determine the extent to which the three societal stigma variables (i.e., State LGBT + Business Climate Index scores, population density where one lives, and access to GM inclusive healthcare) predicted the odds of past-year healthcare mistreatment. Separate models tested the relationship between each of the three societal stigma variables and the two mistreatment variables (i.e., reported past-year healthcare service denial and/or lower quality care in medical settings and in mental health settings). Age, race/ethnicity, sexual orientation, education level, and income were included in all models as covariates. All models were run for each of the three gender identity categories using Stata 15 [30].


Study sample

Participant characteristics are presented in Table 1. A total of 2,031 GM participants were included in these analyses; 55.1% (n = 1,119) were gender-expansive people, 30.3% (n = 626) were transgender men, and 13.8% (n = 280) were transgender women. The mean age of participants was 32.0 years (standard deviation [SD] = 12.2), and the sample was predominantly White (n = 1,836; 91.9%). Nearly two-thirds (64.4%, n = 1,303) of participants had earned a college degree, and half (50.1%, n = 1,014) reported an individual income of less than $20,000 annually. Approximately 89% of our sample lived in a high population density area. The mean State LGBT + Leaders Equality Index score for our sample was 68.99 (SD = 19.08). The mean number of GM people per ‘Leader in LGBTQ Healthcare Equality’-listed hospital was 5,133 (range 871 − 20,892).

Reported past-year denial or lower quality of medical care

On average, 18.8% (n = 378) of GM people reported being denied or given lower quality medical care in the past-year. Within our study groups, 19.4% (n = 215) of gender-expansive people, 19.1% (n = 118) of transgender men, and 16.3% (n = 45) of transgender women reported past-year denial or lower quality medical care. The results of models evaluating societal stigma in relation to reported past-year medical discrimination are presented in Table 2. There was no relationship between societal stigma and reported past-year denial or lower quality medical care among any of the gender identity categories.

Table 2 Results of Models Evaluating Societal Stigma in Relation to Reported Past-Year Mistreatment in Medical Settings

Reported past-year denial or lower quality of mental healthcare

On average, 12.5% (n = 219) of GM people reported being denied or given lower quality mental healthcare in the past-year. Within our study groups, 12.3% (n = 118) of gender-expansive people, 14.6% (n = 80) of transgender men, and 8.6% (n = 21) of transgender women reported past-year mental healthcare denial or lower quality care. The results of models evaluating societal stigma in relation to reported past-year mental healthcare denial or lower quality care are presented in Table 3. There was no relationship between societal stigma and reported past-year mental healthcare denial or lower quality care reported by any of the gender identity categories.

Table 3 Results of Models Evaluating Societal Stigma in Relation to Reported Past-Year Healthcare Mistreatment in Mental Healthcare Settings


Nearly one-fifth of GM people in our sample reported being denied or given lower quality medical care within the past year, with gender-expansive people (19.4%) and transgender men (19.1%) reporting the highest prevalence. While previous research found that transgender men report higher levels of healthcare mistreatment compared to transgender women [6], our findings revealed gender-expansive people are also vulnerable. Although there have been increased efforts to provide gender-affirming services in recent years, these efforts have been focused on supporting a binary construct of gender where medical care enhances gender expression consistent with stereotypical presentation as either man or woman [31, 32]. Transgender women in particular have historically been the focus of healthcare research, which may be why the prevalence of denial or lower quality medical care in this group is somewhat lower, as most healthcare system interventions have been with this group in mind [2]. Further, our sample was predominantly white; we know that GM people of color experience discrimination and other types of mistreatment at greater rates [33,34,35]. Our sample is highly educated although with relatively low annual income compared to more representative samples of GM people [36]. Having greater economic resources implies that participants may have more choices in what providers they see; however, given the lower income of our sample, there may be variations in the types of insurance to which they may have access, such as public sources (e.g., Medicaid) or private insurance; this may impact our findings. People with public insurance in the US have fewer choices, even more so when seeking providers with competency in GM healthcare needs or for accessing gender-affirming interventions [37]. Providers’ lack of awareness of gender-expansive people as a gender minority group and that they may desire gender-affirming interventions can create significant barriers to care engagement [38].

Further, we found that 12.5% of our sample reported denial or lower quality of mental healthcare within the past year with transgender men (14.6%) reporting the highest prevalence, followed by gender-expansive people (12.3%), and transgender women (8.6%). No other study to date, to our knowledge, has independently examined the prevalence of healthcare mistreatment among GM people in mental health settings. Limited available evidence suggests GM people experience enacted stigma, such as discrimination, and in obtaining mental health services [39]. Yet GM people are known to have a high prevalence of depression, suicide, and other mental health disparities [40, 41] and, therefore, are likely to require access to mental health services. Further work to evaluate GM individuals’ experiences in mental health treatment, particularly inpatient psychiatric settings where crisis stabilization treatment is provided, and how mental settings can improve care for GM people is critical to addressing these needs and improving long-term mental health outcomes.

Contrary to our hypotheses, there were no relationships between any variables representing societal stigma and the reports of denial or lower quality care in medical or mental healthcare settings among GM participants. This could be due to the lack of sensitivity and/or specificity our proxy measures of societal stigma. Other forms of stigma, such as individual (self directed stigma or anticipation of stigma) or interpersonal stigma (experiences of stigma), not reflected in our analyses could be better indicators of societal stigma. Our study tested the measures found to be most promising based on previous analyses [15] and the availability of SGM-inclusive healthcare in a state, but we did not find an association between these markers of societal stigma and being denied or given lower quality healthcare. Given our null findings, what could be important is to examine the relationship between societal stigma and efforts to educate healthcare workers to provide inclusive care to GM people. For example, when interventions to improve the abilty of healthcare workers to provide competent care to GM are utilized in a community where negative attitudes toward GM people are prevalent, this could result in less effectiveness as opposed to the same intervention applied in a community where attitudes are more positive. Further, societal stigma could be a predictor of unconscious bias as broader community attitudes could normalize and reinforce stigmatizing behaviors and interactions that may be unintentional. However, currently available variables representing societal stigma are quite imperfect and will require refinement and further research to better define and measure this construct. The role of societal stigma as in efforts to create inclusive health education should be explored. Efforts to improve the education of practicing clinicians (e.g., nurses, physicians) on the healthcare needs of GM people have been made in at least some healthcare facilities [42, 43] and in clinical education [44,45,46,47,48,49]. However, the effects of these efforts may not be enough to counteract the stigmatizing beliefs surrounding gender non-conformity or to consistently combat systemic transphobia. In one study, transphobia (a form of societal stigma) was a stronger predictor of mistreatment of GM people in healthcare settings than cultural competency education [50], indicating that societal stigma could contextualize where there may be variations in the effectiveness of cultural competency education. For example, communities with greater transphobia may be slower to enact cultural competency education and when enacted, it may take longer to influence delivery of patient care. Therefore, development of a measure of community level societal stigma could be a promising representation of the phenomenon [51]. Previous research suggests that lifetime experiences of healthcare discrimination or treatment denial can result in future avoidance or delay of accessing necessary healthcare services [19, 24, 52]. Similarly, structural barriers in the US such as access to health insurance, whether an individual’s policy covers gender affirming treatment, or long wait times may also be impediments to seeking healthcare [53,54,55]. However, structural barriers to mental health services among GM people are understudied [56].

Measurement of healthcare mistreatment in the broader literature on GM people’s experiences is another consideration of our findings. Dichotomous answer options to indicate mistreatment in medical or mental health settings limit the variability in GM people’s reports of their experiences. This is also observed in other studies where whether healthcare was accessed as a yes/no responses and the same for experience discrimination or other types of mistreatment [6, 57, 58]. Some studies evaluated different types of mistreatment in healthcare, but those responses are also reduced to yes/no with little specificity of where the mistreatment occurred, how often, clinicians/support staff involved, or other details that could help guide interventions. Similar barriers were observed in our study where mistreatment was a single question that was asking about two different experiences, “denial or lower quality of care.” A participant who experienced lower quality of care one time in the past year was represented equally with a person who may have experienced both denial and lower quality care many times across the past year. The question did not define lower quality of care, potentially leading to measurement error.

Strengths and limitations

This study discussed the importance of measuring societal stigma distinct from other contructs of stigma and evaluated proxy measures for the construct. We established a prevalence for past-year denial or low-quality care in mental health settings, rarely discussed separately from other types of healthcare mistreatment in the broader literature. We also tested the use of the State LGBT + Business Index as a potential indicator of stigma exposure among GM; no studies, to our knowledge, have evaluated its use in this capacity. Our sample is substantial and represents diverse gender identities across the US, allowing us to perform important subgroup analyses of these distinct gender identitity groups. Despite the importance of this study, limitations remain. The cross-sectional study design limited our ability to determine causality; therefore, our results were correlational. Future work involving longitudal or prospective approaches is an important consideration to advance our understanding of societal stigma and healthcare mistreatment as these differences may be more evident over time as opposed to a singular cross-sectional analysis. Similarly, expanding measurement of societal stigma to be representative of global communities is an important consideration. Some work has looked at country level policies but few look at more localized measures and how those relate to community attitudes [59]. Further, two of our proxies for societal stigma (State LGBT + Business Climate Index, Leaders in LGBTQ Healthcare Equality) included elements that reflected state societal stigma related to sexual orientation and gender identity. While this is relevant to our highly sexually diverse sample (almost 96% sexual minority), future work should examine whether a GM-specific measure of societal stigma could be an improvement. This would particularly be important in a sample with more straight/heterosexual GM participants and to uniquely capture the issues faced by GM people not faced by cisgender SM people. The Leaders in LGBTQ Healthcare Equality variable poses a limitation as it represents LGBTQ inclusivity within inpatient hospital settings. It does not represent the availability of inclusive and affirming outpatient care, which could be disproportionate to the number of hospitals given this designation (e.g., few hospitals may have the designation, but there may be more GM-inclusive outpatient resources and on the whole more healthcare for LGBTQ + people may occur in outpatient sites). Sample recruitment relied on convenience sampling; therefore, our sample was not representative of the broader GM population. Most specifically, we had a high proportion of white participants who were highly educated with relatively high income, which is considerably different than estimations of the broader GM population [6, 60]. GM people of color face higher rates of discrimination within and outside of healthcare [2], thus the sample composition likely impacted our results. Our sample was composed of GM adults, who may have had different experiences in accessing medical or mental healthcare than GM young adults or youth. Similarly, our sample lived predominantly in higher population density areas, leading to less granularity in our analyses to differentiate experiences of GM people in rural settings. Therefore, our findings were not generalizable to those populations. Further, any measure of societal stigma should be tested among a diverse sample due to the multiple forms of oppression experienced by individuals with multiple minoritized identities (e.g., one who is GM and sexual minority, one who is GM and Black; GM people who are immigrants or refugees [56, 57]. The focus on mistreatment in medical and mental health settings broadly may obscure understanding of differences between care environments in which GM individuals have experienced healthcare mistreatment such as medical laboratories or pharmacies in contrast to healthcare provider offices [38]. Further work asking about experiences in specific healthcare settings may address this gap and form targeted opportunities for intervention and evaluation.

Future directions

Future studies should explore the use of electronic health records to evaluate the care GM patients receive for specific conditions and allow for a nuanced comparison with cisgender patients in combination with self-report measures. Continued improvement is needed in the measurement of societal stigma. Our results suggest that societal stigma is not associated with reported healthcare service denial or lower quality of care of GM people; but this could be due to the specific measures used to assess societal stigma and denial/quality of care. For example, the State LGBT + Business Climate Index is composed of items that measure structural conditions (e.g.., Legal and Nondiscrimination Protections) and societal stigma (e.g., political and religious attitudes). Other existing measures of attitudes toward transgender people cannot be disaggregated by state. As such, routine collection of individuals’ attitudes toward GM people in large, nationally representative samples could help us measure societal attitudes directly. The ability to identify state of residence of respondents in association with attitudes is important. Societal attitudes, positive or negative, may be enacted through state-level policies. General attitudes in a particular area could shift, but changes to state-level policies could lag. Examples of this have been observed such as when the “bathroom bills” (i.e., legislation requiring people to use bathrooms as designated based on one’s sex assigned at birth) were a focus of several state’s legislative sessions yet were unpopular with the US public [61].


GM people continue to experience both denial and lower quality of care in medical and mental healthcare settings. Despite less societal stigma in some areas, no difference was observed using the potential measures of societal stigma. Mistreatment in mental health settings is an important area for focused research among GM people who have considerable disparities in mental health outcomes. Further research that employs more nuanced and detailed measures of mistreatment in healthcare broadly is needed to improve the healthcare experiences of GM people, and these relationships should be evaluated in diverse GM study populations globally and in communities.

Data Availability

The PRIDE Study is a community-based research project. LGBTQ + populations have historically been marginalized, which has impacted the trust between communities and institutions. Therefore, part of the guidelines of The PRIDE Study is restricted access to the participants’ data. Access to the data can be requested by submitting an ancillary study application at and following the application process.



Gender minority


Lesbian, gay, bisexual, transgender, and other related sexual orientations and gender identities that are not heterosexual or cisgender (i.e., one whose gender is the same as that which is traditionally associated with their sex assigned at birth).


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The PRIDE Study is a community-engaged research project that serves and is made possible by LGBTQ + community involvement at multiple points in the research process, including the dissemination of findings. We acknowledge the courage and dedication of The PRIDE Study participants for sharing their stories; the careful attention of PRIDEnet Participant Advisory Committee (PAC) members for reviewing and improving every study application; and the enthusiastic engagement of PRIDEnet Ambassadors and Community Partners for bringing thoughtful perspectives as well as promoting enrollment and disseminating findings. For more information, please visit Certain data used for this research has been provided by the Human Rights Campaign Foundation (“HRCF”) and used with permission. Future requests for the data should be directed to HRCF.


Open access funding provided by Uppsala University. KDC was supported in part by the National Institute of Nursing Research (Grant 1F31NR019000-01). JS was supported by the National Institute on Drug Abuse (K24 DA051328). JOM was partially supported by grant K12DK111028 from the National Institute of Diabetes, Digestive, and Kidney Disorders. AF was supported by the National Institute on Drug Abuse (K23DA039800). Research reported in this article was partially funded through a Patient-Centered Outcomes Research Institute (PCORI, Award (PPRN-1501-26848) to MRL. The statements in this article are solely the responsibility of the authors and do not necessarily represent the views of PCORI, its Board of Governors or Methodology Committee, or the National Institutes of Health.

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Drs. K.D.C. and A.F. conceived the study and study design, with input from M.R.L, M.A.T., J.D.B., and J.O.M. Dr. A.F. supervised all analyses. All statistical analyses were completed by Dr. K.D.C., who also led the article writing. All coauthors were involved with review and interpretation of results. All coauthors reviewed and approved the current article.

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Correspondence to Kristen D. Clark.

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Competing interests

JOM has consulted for Sage Therapeutics (5/2017) in a one-day advisory board, Ibis Reproductive Health (a non-for-profit research group; 3/2017-5/2018, 2020-present), Hims Inc. (2019 - present), and Folx Inc (2020-present). MRL has consulted for Hims Inc. (2019 - present) and Folx, Inc. (2020). The remaining authors have no conflicts to disclose.

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This study was reviewed and approved by the Stanford University and University of California San Francisco institutional review boards. Upon enrollment in The PRIDE Study, participants were provided with informed consent which they then affirmed electronically.

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Clark, K.D., Lunn, M.R., Bosse, J.D. et al. Societal stigma and mistreatment in healthcare among gender minority people: a cross-sectional study. Int J Equity Health 22, 162 (2023).

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