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Table 3 Bivariate analyses of inpatient mortality with patient-, inpatient care unit-, and municipality-level variables

From: COVID-19 inpatient mortality in Brazil from 2020 to 2022: a cross-sectional overview study based on secondary data

Variable

N

%

Dead

Alive

N

%

N

%

Inpatient care unit category

 Public SUS

632,024

39.1

236,743

37.5

395,281

62,5

 Public non-SUS

13,599

0.8

4,379

32.2

9,220

67,8

 Private SUS

70,175

4.3

22,431

32.0

47,744

68,0

 Private non-SUS

346,035

21.4

85,092

24.6

260,943

75,4

 Philanthropic SUS

475,456

29.4

152,856

32.1

322,600

67,9

 Philanthropic non-SUS

78,139

4.8

16,679

21.3

61,460

78,7

Age (years)

 18-39

236,245

14.6

29,899

12.7

206,346

87,3

 40-49

252,554

15.6

46,308

18.3

206,246

81,7

 50-59

318,693

19.7

82,185

25.8

236,508

74,2

 60-69

319,674

19.8

118,350

37.0

201,324

63,0

 70-79

267,762

16.6

122,926

45.9

144,836

54,1

 ≥ 80

220,500

13.6

118,512

53.7

101,988

46,3

Sex

 Female

719,502

44.5

227,286

31.6

492,216

68,4

 Male

895,789

55.5

290,842

32.5

604,947

67,5

 Unknown

137

0.0

52

38.0

85

62,0

Race/color

 White

713,807

44.2

230,070

32.2

483,737

67,8

 Black

64,697

4.0

24,495

37.9

40,202

62,1

 Asian

15,367

1.0

4,850

31.6

10,517

68,4

 Mixed race

518,786

32.1

176,611

34.0

342,175

66,0

 Indigenous

2,528

0.2

878

34.7

1,650

65,3

 Unknown

300,243

18.6

81,276

27.1

218,967

72,9

Education

 No schooling

34,439

2.1

17,405

50.5

17,034

49,5

 Primary

153,134

9.5

66,065

43.1

87,069

56,9

 Lower secondary

109,540

6.8

40,228

36.7

69,312

63,3

 Upper secondary

190,215

11.8

53,020

27.9

137,195

72,1

 Tertiary

92,573

5.7

22,318

24.1

70,255

75,9

 Unknown

1,035,527

64.1

319,144

30.8

716,383

69,2

COVID-19 symptoms

 < 5

917,282

56.8

295,066

32.2

622,216

67,8

 ≥ 5

698,146

43.2

223,114

32.0

475,032

68,0

Comorbidity – obesity

 Yes

135,333

8.4

51,105

37.8

84,228

62,2

 No

1,480,095

91.6

467,075

31.6

1,013,020

68,4

Comorbidity – cardiopathy

 Yes

530,766

32.9

216,064

40.7

314,702

59,3

 No

1,084,662

67.1

302,116

27.9

782,546

72,1

Comorbidity – diabetes

 Yes

372,910

23.1

154,371

41.4

218,539

58,6

 No

1,242,518

76.9

363,809

29.3

878,709

70,7

Comorbidity – hematologic disease

 Yes

10,842

0.7

4,817

44.4

6,025

55,6

 No

1,604,586

99.3

513,363

32.0

1,091,223

68,0

Comorbidity – Down syndrome

 Yes

3,928

0.2

1,613

41.1

2,315

58,9

 No

1,611,500

99.8

516,567

32.1

1,094,933

67,9

Comorbidity – hepatic disease

 Yes

13,017

0.8

6,639

51.0

6,378

49,0

 No

1,602,411

99.2

511,541

31.9

1,090,870

68,1

Comorbidity - asthma

 Yes

38,953

2.4

11,092

28.5

27,861

71,5

 No

1,576,475

97.6

507,088

32.2

1,069,387

67,8

Comorbidity – pneumopathy

 Yes

54,712

3.4

27,368

50.0

27,344

50,0

 No

1,560,716

96.6

490,812

31.4

1,069,904

68,6

Comorbidity – neurologic disease

 Yes

58,806

3.6

30,108

51.2

28,698

48,8

 No

1,556,622

96.4

488,072

31.4

1,068,550

68,6

Comorbidity – kidney disease

 Yes

59,105

3.7

31,718

53.7

27,387

46,3

 No

1,556,323

96.3

486,462

31.3

1,069,861

68,7

Comorbidity – immunodepression

 Yes

39,630

2.5

18,366

46.3

21,264

53,7

 No

1,575,798

97.5

499,814

31.7

1,075,984

68,3

Comorbidity – other disease

 Yes

452,071

28.0

180,210

39.9

271,861

60,1

 No

1,163,357

72.0

337,970

29.1

825,387

70,9

Number of comorbidities

 0

602,521

37.3

130,978

21.7

471,543

78,3

 1

487,026

30.1

157,975

32.4

329,051

67,6

 2

347,052

21.5

140,916

40.6

206,136

59,4

 3

137,124

8.5

65,462

47.7

71,662

52,3

 ≥ 4

41,705

2.6

22,849

54.8

18,856

45,2

ICU use

 Yes

580,789

36.0

323,627

55.7

257,162

44,3

 No

1,034,639

64.0

194,553

18.8

840,086

81,2

Ventilatory support use

 Yes, invasive

304,150

18.8

232,945

76.6

71,205

23,4

 Yes, non-invasive

832,351

51.5

190,548

22.9

641,803

77,1

 No

288,385

17.9

33,824

11.7

254,561

88,3

 Unknown

190,542

11.8

60,863

31.9

129,679

68,1

Length of stay (days)

 0

32,688

2.0

19,847

60.7

12,841

39,3

 ≥1

1,519,154

94.0

489,477

32.2

1,029,677

67.8

 Unknown

63,586

3.9

8,856

13.9

54,730

86,1

Patient residence city’s HDI

 Very low (<0.500)

1,232

0.1

327

26.5

905

73,5

 Low (0.500-0.599)

54,924

3.4

20,938

38.1

33,986

61,9

 Medium (0.600-0.699)

196,998

12.2

71,437

36.3

125,561

63,7

 High (0.700-0.799)

969,716

60.0

317,107

32.7

652,609

67,3

 Very high (≥0.800)

392,558

24.3

108,371

27.6

284,187

72,4

Inpatient care unit’s COVID-19 hospitalizations 2020-2022

 100-299

159,081

9.8

57,993

36.5

101,088

63,5

 300-599

237,066

14.7

81,593

34.4

155,473

65,6

 600-999

287,125

17.8

93,523

32.6

193,602

67,4

 1000-3999

762,847

47.2

230,365

30.2

532,482

69,8

 ≥ 4000

169,309

10.5

54,706

32.3

114,603

67,7

Hospital beds

 < 30

68,187

4.2

18,704

27.4

49,483

72,6

 30-49

107,077

6.6

29,718

27.8

77,359

72,2

 50-99

290,920

18.0

84,583

29.1

206,337

70,9

 100-199

535,855

33.2

172,358

32.2

363,497

67,8

 200-399

389,708

24.1

132,935

34.1

256,773

65,9

 ≥ 400

210,175

13.0

74,642

35.5

135,533

64,5

 Unknown

13,506

0.8

5,240

38.8

8,266

61,2

Healthcare unit type

 General hospital

1,521,877

94.2

484,267

31.8

1,037,610

68,2

 Specialized hospital

49,615

3.1

17,772

35.8

31,843

64,2

 Mixed unit

9,880

0.6

2,810

28.4

7,070

71,6

 General emergency center

25,775

1.6

10,258

39.8

15,517

60,2

 Specialized emergency center

8,281

0.5

3,073

37.1

5,208

62,9

Country macro-region

 North

99,365

6.2

35,872

36.1

63,493

63,9

 Northeast

247,242

15.3

90,521

36.6

156,721

63,4

 Southeast

803,598

49.7

253,971

31.6

549,627

68,4

 South

301,996

18.7

90,536

30.0

211,460

70,0

 Midwest

163,227

10.1

47,280

29.0

115,947

71,0

Inpatient care’s city

 Same of patient’s residence

1,146,988

71.0

355,753

31.0

791,235

69,0

 In patients’ residence Health Region

250,997

15.5

87,259

34.8

163,738

65,2

 Another Health Region

217,443

13.5

75,168

34.6

142,275

65,4

 Inpatient care unit’s city size

 <20000 inhabitants

32,636

2.0

6,601

20.2

26,035

79,8

 20000-49999 inhabitants

122,254

7.6

34,725

28.4

87,529

71,6

 50000-99999 inhabitants

166,215

10.3

53,954

32.5

112,261

67,5

 100000-999999 inhabitants

696,049

43.1

232,920

33.5

463,129

66,5

 ≥ 1000000 inhabitants

598,274

37.0

189,980

31.8

408,294

68,2

Pandemic period

 Feb 2020 – Mai 2020 (wave 1.1)

121,022

7.5

44,440

36.7

76,582

63.3

 Jun 2020 – Ago 2020 (wave 1.2 - expansion)

196,019

12.1

63,447

32.4

132572

67.6

 Sep 2020 – Nov 2020

136,103

8.4

396,24

29.1

96,479

70,9

 Dec 2020 – Fev 2021 (wave 2.1)

273,395

16.9

912,73

33.4

182,122

66,6

 Mar 2021 – Apr 2021 (wave 2.2)

329,850

20.4

119,572

36.3

210,278

63,7

 May 2021 – Jun 2021 (wave 2.3)

254,463

15.8

70,480

27.7

183,983

72,3

 Jul 2021 – Dec 2021

151,421

9.4

44,646

29.5

106,775

70,5

 Jan 2022 – Feb 2022 (wave 3)

81,595

5.1

26,706

32.7

54,889

67,3

 Mar 2022 – Dec 2022

71,560

4.4

17,992

25.1

53,568

74,9

  1. Source: SIVEP Gripe - Sistema de Informação de Vigilância Epidemiológica da Gripe
  2. The study excluded inpatient care units with less than 100 COVID-19 hospitalizations in the period