A survey of availability, price and affordability of essential medicines from 2011 to 2016 in Chinese secondary and tertiary hospitals

Table 4 Results of Wilcoxon rank-sum test: median MPR for innovator brand medicines and generic medicines

Year	Innovator brand medicines (n = 16)		Generic medicines (n = 16)		MPR_IB	P
Year	MPR	Product specific ΔMPR	MPR	Product specific ΔMPR	MPR_G	P
2011	29.51		8.06		3.66	0.000
2012	33.07	2.11	8.28	−0.02	3.99	0.000
2013	37.20	2.15	7.18	0.12	5.18	0.000
2014	36.57	−0.80*	7.05	−0.14*	5.19	0.000
2015	28.07	−0.85*	5.77	−0.16*	4.86	0.002
2016	34.76	−0.85	5.50	−0.08	6.32	0.000

^*P < 0.05
MPR_IB MPR of innovator brand medicines, MPR_G MPR of generic medicines
Product specific Δ MPR: first calculated the differences of MPR of each product between adjacent years and then chose the median value of these differences as Product specific Δ MPR

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