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Table 2 Diabetes/obesity top 10 interventions

From: Setting priorities for knowledge translation of Cochrane reviews for health equity: Evidence for Equity

 

Intervention

Outcome

Feasibilitya

Deliverabilityb

Universalityc

Effect on Equityd

Overall Rating (%)

1

Sulphonylureas versus insulin

All-cause mortality; best-worst case scenario

Range: 2–4 Total: 75 Rank: 3

Range: 2–4 Total: 75 Rank: 1

Range: 2–4 Total: 75 Rank: 5

Range: 2–4 Total: 70.83 Rank:7

76.67 Rank: 1

2

metformin vs sulphonylureas or insulin.

all cause mortality

Range: 2–4 Total: 87.5 Rank: 1

Range: 2–4 Total: 66.67 Rank: 5

Range: 2–4 Total: 75 Rank: 5

Range: 2–4 Total: 70.83 Rank: 7

75 Rank: 2

3

ACEi versus placebo/no treatment

All cause mortality

Range: 2–4 Total: 80 Rank: 2

Range: 2–4 Total: 75 Rank:1

Range: 3–4 Total: 85 Rank: 1

Range: 2–3 Total: 70 Rank: 8

71.15 Rank: 3

4

Low salt vs high salt diet

Systolic BP

Range: 1–3 Total: 62.5 Rank: 9

Range: 1–4 Total: 71.88 Rank: 2

Range: 2–3 Total: 59.38 Rank: 14

Range: 2–4 Total: 71.88 Rank: 5

77.5 Rank: 4

5

Exercise vs no exercise

Glycated haemoglobin (%)

Range: 1–3 Total: 62.5 Rank: 9

Range: 2–4 Total: 71.88 Rank: 2

Range: 2–3 Total: 71.88 Rank: 6

Range: 2–3 Total: 68.75 Rank: 9

73 Rank: 5

6

Group-based diabetes education programme versus individual routine treatment

reduction in diabetes medication

Range: 1–4 Total: 53.13 Rank: 15

Range: 2–4 Total: 68.75 Rank: 4

Range: 2–3 Total: 65.63 Rank: 9

Range: 2–4 Total: 81.25 Rank: 1

73 Rank: 5

7

Effects of intensive versus brief education in high risk patient samples

Foot ulcer incidence (1-year follow-up)

Range: 1–3 Total: 50 Rank: 16

Range: 2–4 Total: 65.63 Rank: 6

Range: 2–4 Total: 65.63 Rank: 9

Range: 2–4 Total: 78.13 Rank: 3

71 Rank: 6

8

Tight-moderate versus loose glycaemic control

Pre-eclampsia

Range: 0–3 Total: 46.43 Rank: 18

Range: 0–3 Total: 50 Rank: 19

Range: 0–3 Total: 53.57 Rank: 18

Range: 0–3 Total: 53.57 Rank: 18

70.31 Rank: 7

Very tight versus tight-moderate glycaemic control

Maternal hospitalisation (days)

Tight versus moderate glycaemic control

Maternal hypoglycaemia in first half of pregnancy

9

low glycaemic index (LGI) vs high glycaemic index

large-for-gestational age

Range: 2–4 Total: 68.75 Rank: 5

Range: 2–4 Total: 75 Rank: 1

Range: 2–4 Total: 78.13 Rank: 4

Range: 2–4 Total: 78.13 Rank: 3

67 Rank: 8

10

ACEi versus placebo/no treatment

Systolic BP

Range: 2–4 Total: 75 Rank: 3

Range: 2–4 Total: 68.75 Rank: 4

Range: 2–4 Total: 75 Rank: 5

Range: 2–3 Total: 68.75 Rank: 9

65.38 Rank: 9

  1. aIs there sufficient capacity to implement the intervention? Is it feasible to provide required training to staff? Rankings are 0 to 4. 4 = optimal (easier to implement), 0 = more difficult
  2. bConsider the level of difficulty with intervention delivery, the infrastructure required (human resources, facilities, etc.). Consider the resources available and whether the intervention is affordable. Rank 0–4, 4 = optimal (easier/fewer health system effects), 0 = more difficult/greater health system effects,
  3. cIs the intervention relevant to most countries? Rankings are 0 to 4. 4 = Optimal (more generalizable/population-based, 0 = less generalizable/specific population
  4. dDoes the distribution of the disease burden affect mainly the disadvantaged? Are the disadvantaged most likely to benefit from the intervention? Will the intervention improve equity in disease burden distribution long-term? Rankings are 0 to 4. 4 = Optimal (more generalizable/population-based, 0 = less generalizable/specific population