Table 3 GRADE evidence profile for family-level domains
Domain | Number of studies | Risk of bias | Inconsistency | Effect size | Quality | Comments |
|---|---|---|---|---|---|---|
Family cohesion (positive) | 12 | No serious risk | No serious inconsistency | Small-large | Moderate | Rated up due to evidence of a dose-gradient effect |
Low family SES | 8 | No serious risk | Serious inconsistency | Inconsistent | Very low | Rated down due to inconsistent findings |
Atypical family structure | 6 | No serious risk | No serious inconsistency | Negligible-small | Moderate | Rated up due to control of confounding factors |
Caregiver mental health/behaviour (negative) | 8 | No serious risk | No serious inconsistency | Small-large | Moderate | Rated up due to control of confounding factors |
Family cohesion (negative) | 6 | No serious risk | No serious inconsistency | Medium-large | High | Rated up due to medium-large effect sizes and a dose-gradient effect |