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Table 1 Estimates of baseline trend, level and trend changes, and absolute changes one year after the policy interventions for total antipsychotic sales and for generic market share of major active substances in Finland and Portugal

From: Impact of pharmaceutical policy interventions on utilization of antipsychotic medicines in Finland and Portugal in times of economic recession: interrupted time series analyses

 

Variable

Monthly baseline trend pre-policy

Level change post-policy

Monthly trend change post-policy

Absolute estimated change one year post-policy

(unit)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Finland

Total sales growth per 100,000 population (SU)

704 (519, 889)

-

-273 (-572, 26)

-3550 (-7354, 254)

Quetiapine generic market share (%)

2.07 (1.97, 2.17)

33.61 (31.61, 35.61)

-2.06 (-2.18, -1.95)

6.80 (3.92, 9.68)

Risperidone generic market share (%)

2.19 (2.03, 2.34)

37.65 (34.60, 40.69)

-2.04 (-2.20, -1.88)

11.13 (6.79, 15.48)

Clozapine generic market share (%)

0.07 (-0.02, 0.17)

2.22 (0.30, 4.14)

-0.25 (-0.36, -0.13)

-0.97 (-3.75, 1.81)

Portugal

Total sales growth per 100,000 population (SU)

-

-4686 (-8913, -458)

-

-4686 (-8758, -613)

Risperidon generic market share (%)

-0.08 (-0.15, 0.01)

2.16 (0.76, 3.57)

0.19 (0.06, 0.31)

4.59 (2.67, 6.51)

Amisulpride generic market share (%)

-

12.23 (9.61, 14.85)

0.82 (0.56, 1.09)

22.95 (21.01, 24.90)

  1. CI = confidence interval, SU = standard unit.
  2. Data source: IMS MIDAS®, January 2007 and December 2011, IMS Health Incorporated. All Rights Reserved.