Inclusion criteria | |
● | High CVD risk (5-year CVD risk equal or greater than 15%, either on the basis of a documented history of CVD or estimated from the NZ modified Framingham equation [16]) |
● | All polypill ingredients indicated |
● | Uncertainty whether therapy best provided as a polypill or with usual care |
● | Participant able to give informed consent |
Exclusion criteria | |
● | Age under 18 years |
● | Age over 80 years (or over 70 years for men with no history of CVD because the risks of aspirin may be greater than the benefits of aspirin in this population [17]) |
● | Contraindication to polypill component |
● | Congestive heart failure |
● | Medication change unsuitable for patient |