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Table 1 Baseline characteristics of syphilis-seropositive pregnant women with treatment or treatment failure during pregnancy in Guangzhou, China, 2014–2016 (N = 1248)

From: Factors influencing treatment status of syphilis among pregnant women: a retrospective cohort study in Guangzhou, China

Variable

Women with untreated or inadequately treated

N(%)

Women with adequately treated

N(%)

Total

N(%)

P-valuea

Number

379 (30.4)

869 (69.6)

1248

 

Age in years, mean ± SD

30.2 ± 6.4

30.4 ± 5.7

30.3 ± 6.0

0.488b

Residence

   

< 0.001

 Local

68 (18.5)

300 (81.5)

368 (29.5)

 

 Migrant

311 (35.3)

569 (64.7)

880 (70.5)

 

Marital status

   

< 0.001

 First marriage

263 (26.5)

729 (73.5)

992 (79.5)

 

 Unmarried

71 (50.0)

71 (50.0)

142 (11.4)

 

 Others

45 (39.5)

69 (60.5)

114 (9.1)

 

Education

   

< 0.001

 Middle school or less

239 (35.1)

442 (64.9)

681 (54.6)

 

 High school and higher

100 (21.7)

362 (78.4)

462 (37.0)

 

 Unknown

40 (38.1)

65 (61.9)

105 (8.4)

 

Occupation

   

< 0.001

 Officer / Business / Service industry

25 (15.3)

138 (84.7)

163 (13.1)

 

 Farmer

41 (26.3)

115 (73.7)

156 (12.5)

 

 Unemployed or Others or Unknown

313 (33.7)

616 (66.3)

929 (74.4)

 

Multipara

   

< 0.001

 No

78 (17.9)

359 (82.2)

437 (35.0)

 

 Yes

300 (37.3)

505 (62.7)

805 (64.5)

 

 Unknown

1 (16.7)

5 (83.3)

6 (0.5)

 

History of adverse pregnancy outcome

  

0.020

 No

316 (31.9)

674 (68.1)

990 (79.3)

 

 Yes

63 (24.4)

195 (75.6)

258 (20.7)

 

History of syphilis infection

   

< 0.001

 No

267 (35.2)

492 (64.8)

759 (60.8)

 

 Yes

112 (22.9)

377 (77.1)

489 (39.2)

 

Time of syphilis diagnose (gestational age, weeks)

   

 < 28w or pre-pregnancy

58 (6.9)

781 (93.1)

839 (67.2)

 

 ≥ 28w

321 (78.5)

88 (21.5)

409 (32.8)

 

Current staging of syphilis infection

  

0.125

 Latent

302 (29.9)

708 (70.1)

1010 (80.9)

 

 Primary / Secondary / Tertiary

18 (24.0)

57 (76.0)

75 (6.0)

 

 Unknown

59 (36.2)

104 (63.8)

163 (13.1)

 

Non-treponemal serum test titer

  

0.001

 < 1:8

297 (28.4)

750 (71.6)

1047 (83.9)

 

 ≥ 1:8

69 (39.0)

108 (61.0)

177 (14.2)

 

 Unknown

13 (54.2)

11 (45.8)

24 (1.9)

 

Location of diagnosing hospital

   

0.002

Urban

107 (25.9)

306 (74.1)

413 (33.1)

 

 Suburban

157 (36.4)

274 (63.6)

431 (34.5)

 

 Rural

115 (28.5)

289 (71.5)

404 (32.4)

 

Type of diagnosing hospital

   

< 0.001

 Public

341 (29.1)

832 (70.9)

1173 (94.0)

 

 Private

38 (50.7)

37 (49.3)

75 (6.0)

 

Grade of diagnosing hospital

   

< 0.001

 Township

122 (40.7)

178 (59.3)

300 (24.0)

 

 District

103 (27.8)

267 (72.2)

370 (29.7)

 

 Municipal / Provincial

154 (26.6)

424 (73.4)

578 (46.3)

 
  1. Abbreviations: SD, standard deviation.
  2. a: Chi-square tests; b: T-test;