Preventing early childhood transmission of hepatitis B in remote Aboriginal communities in northern Australia

Table 3 Hepatitis B status of all child participants and characteristics of children with chronic hepatitis B and children who were immune by exposure

Hepatitis B status of child participants with complete serology^a
Status				Number (n = 33)		% (95% CI)
Immune by vaccination				12		36.4 (20.4–54.9)
Immune by exposure				3		9.1 (1.9–24.3)
Chronic hepatitis B infection				3		9.1 (1.9–24.3)
Isolated anti-HBc positive				2		6.1 (0.7–20.2)
Non-immune				13		39.4 (22.9–57.9)
Characteristics of children with chronic hepatitis B (1–3) and children who were immune by exposure (4–8)
Child	Gender	Gestational Age (weeks)	Weight (kg)	Mode of delivery	Mother’s age at time of birth	Fully vaccinated^b	HBIg documented as given at birth	Transmission
1^c	Female	35	2.2	Vaginal	24.9	No	Yes	Vertical (WGS)
2	Female	34	1.8	Vaginal	17.4	Yes	Yes	?
3	Male	32	1.4	Vaginal	21.9	Yes	Yes	?
4	Female	35	2.2	Vaginal	24.9	No	Yes	?
5^d	Female	No details	No details	No details	32.6	Yes	Yes	Horizontal
6^d	Female	38	3.5	Vaginal	27.6	No	Yes	?
7	Female	40	3.6	Vaginal	21.1	No	No	?
8	Female	39	2.6	Caesarean	32.3	No	Yes	?

^aOf the remaining 5 without complete serology, 2 had no serology, 1 had anti-HBc and anti-HBs performed only (and was anti-HBs positive, cAb negative), 1 had anti-HBs done only (positive), and 1 had HBsAg and anti-HBs done only (HBsAg negative, sAb positive)
^bbirth dose given and three vaccines prior to 12 months of age given at appropriate intervals
^cchild’s virus isolate whole genome sequenced
^disolated core antibody positive

ISSN: 1475-9276