Table 3 Adjusted Cox regression model^a for the survival of children with acute lymphoblastic leukemia (2007–2009 cohorts)

 Maximum educational level (parents)

University degree or higher

(Reference group)

Bachelor’s/technical degree

0.6 (0.37, 1.13)

High school

0.7 (0.35, 1.22)

Primary school or less

1.0 (0.41, 2.28)

 Monthly family income level

4th quartile

(Reference group)

3rd quartile

1.8 (0.99, 3.09)

2nd quartile

1.6 (0.90, 2.95)

1st quartile

1.1 (0.59, 2.21)

 Availability of basic services in the home

All three present

(Reference group)

At least one not present

1.9 (1.00, 3.75)*

 Maximum occupational level (parents)

Managers and professionals

(Reference group)

Mid-level and support workers

1.4 (0.65, 2.89)

Service, sales and skilled workers

1.3 (0.55, 3.04)

Machine operators; unskilled laborers and unemployed

0.8 (0.34, 2.09)

 Proportion of minor’s life insured by IMSS prior to ALL diagnosis

80–100%

(Reference group)

50 to < 80%

1.3 (0.74, 2.41)

25 to < 50%

2.2 (1.18, 4.28)*

< 25%

2.4 (1.35, 4.42)*

 Age at ALL diagnosis (years)

< 1

3.1 (1.21, 7.81)*

1 to < 5

(Reference group)

5 to < 10

0.9 (0.55, 1.51)

10 to < 15

0.9 (0.48, 1.70)

 Sex

Female

(Reference group)

Male

1.0 (0.69, 1.52)

 ALL risk diagnosis

Standard risk

(Reference group)

High risk

1.3 (0.81, 2.20)

 Diagnosis cohort

2007

(Reference group)

2008

0.7 (0.45, 1.19)

2009

1.0 (0.63, 1.56)

 Network of services

La Raza network

(Reference group)

SXXI network

0.7 (0.31, 1.36)

 Interaction: diagnosis risk and medical service network

No high risk in SXXI network

(Reference group)

High risk in SXXI network

2.6 (1.12, 5.95)*

 Distance from tertiary hospital (km)

< 20

(Reference group)

20 to < 50

1.0 (0.65, 1.60)

50 to < 200

0.9 (0.52, 1.70)

≥200

0.7 (0.25, 1.73)

 Type of secondary hospital

Hospital General Regional

(Reference group)

Hospital General de Zona

0.9 (0.59, 1.52)

Hospital General de Subzona

2.0 (0.55, 7.15)